Brizoline

Country of origin: Russia
Pharm-Group: Agents that stimulate alpha and beta adrenergic receptors

Manufacturers: Bryntsalov-A (Russia)
International name: Xylometazoline
Synonyms: Galazolin, Grippostad Rino, Dlynos, Doctor Theiss Nazolin, Xylene, Xylobene, Xylometazoline, Xymelin, Nasal aerosol, Nazenspray E-ratiopharm, Nazenspray K-ratiopharm, Olint, Otrivin, Rinonorm, Rinostop, Tizin xylo, Farmazolin
Dosage forms: nasal drops 0.05%, nasal drops 0.1%
Composition: Active substance - xylometazoline.

Indications for use: Acute allergic rhinitis, hay fever, sinusitis, otitis media (to reduce swelling of the nasopharyngeal mucosa); preparing the patient for diagnostic procedures in the nasal passages.

Contraindications: Hypersensitivity, arterial hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, hyperthyroidism, pregnancy, breastfeeding.

Side effects: With frequent or prolonged use - irritation of the mucous membrane, burning, tingling, sneezing, dryness, hypersecretion. Rarely - swelling of the nasal mucosa, palpitations, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disturbance, visual disturbances. With long-term use of high doses - depression.

Interaction: Incompatible with MAO inhibitors and tricyclic antidepressants.

Overdose: Symptoms: increased side effects. Treatment: symptomatic.

Special instructions: The aerosol is used in children under 3 years of age. Nasal drops with a concentration of the active substance of 1 mg/ml for children under 2 years of age are prescribed only by a doctor. Should not be used for a long time (for example, for chronic rhinitis). For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.

Literature:

1. Encyclopedia of Medicines 2004.
2. Encyclopedia of Medicines 2003.