Burkitt's Lymphoma

Burkitt's lymphadrematosis is one of the non-Hodgkin's lymphomas, the most common among malignant neoplasms of lymphatic tissue. More than 85% of lymphomas in this category are the so-called diffuse variant of the disease, in which they have the appearance of diffuse infiltration of the lymph nodes and bone marrow with extranodal lesions in various organs (hearts, brain, kidneys) and the membranes of the spinal cord and brain. This option also occurs in

Berkitto's lymphomas are lymphoproliferative diseases that occur predominantly in children and adolescents, in some cases associated with immunodeficiency. BLC are B-cell lymphomas characterized by the expression of clonal surface IgM; the clone is limited to the mu class (normally, less than 0.1% of plasma cells carrying the surface mu chain are present in the blood). In typical cases, tumors resembling lymphadenopathy are formed in the periphery, and in some cases, single or multiple extranodal foci are formed. The duration of the disease ranges from 7 months to 16 years. Metastases are detected in less than 10% of cases. Oral cavity involvement is described in more than 20% of cases.