Dilkoran 80

Country of origin: Yugoslavia

Pharm-Group: Antianginal agents - nitrates and nitrites

Manufacturers: Inex Hemofarm (Yugoslavia)

International name: Pentaerythrityl tetranitrate

Synonyms: Pentalong, Erinite

Dosage forms: retard tablets 80 mg

Composition: Active substance - Pentaerythrityl tetranitrate.

Indications for use: Chronic heart failure (as part of complex therapy), angina pectoris (prevention).

Contraindications: Hypersensitivity, severe arterial hypotension, collapse, shock; acute myocardial infarction with arterial hypotension; traumatic brain injury, angle-closure glaucoma, cerebrovascular accident (especially hemorrhagic stroke).

Side effect:

1. From the nervous system and sensory organs: headache, dizziness, tinnitus, weakness, increased fatigue, anxiety.

2. From the cardiovascular system and blood: decreased blood pressure, orthostatic hypotension, tachycardia.

3. From the gastrointestinal tract: nausea, diarrhea.

4. Other: allergic reactions, increased sweating.

Interaction:

1. Propranolol enhances the antianginal effect.

2. Dihydroergotamine may reduce the antianginal effect.

Overdose: No information.

Special instructions:

1. During therapy it is necessary to avoid alcohol consumption.

2. With long-term therapy, tolerance may develop; the risk of addiction is reduced when taken once a day in combination with other antianginal drugs.

3. Not used to relieve angina attacks due to the slow development of the effect.

Literature:

1. Encyclopedia of Medicines, 2004
2. Directory "Medicines", M.A. Klyuev, 2001