Epithelial Nests of Brunn

Epithelial nests of Brunn

Epithelial nests of Brunn are one of the structures associated with the epithelium of the mucous membrane of the respiratory tract. They are named after the Swedish anatomist and physiologist Johan Brunn, who first described these formations in 1787.

Brunn's epithelial nests are glandular structures located in the mucous layer of the respiratory tract. They consist of cells that secrete mucosa, a viscous fluid that plays an important role in protecting and moistening the airways.

The functions of Brunn's epithelial nests are closely related to their structure and secretory activity. They perform the following tasks:

1. Moisturizing the airways: The mucus-producing cells of Brunn's epithelial nests produce mucosis, which coats the inner surface of the airways. This helps to humidify the inhaled air and prevents the mucous membrane from drying out.

2. Protection against harmful substances: The mucose secreted by the epithelial nests of Brunn contains many antimicrobial factors such as lysozyme and immunoglobulins. They help fight infections and protect the respiratory tract from harmful microorganisms.

3. Airway Clearance: Mucosa produced by the epithelial nests of Brunn also contains cilia, small hair-like structures that move rhythmically. These movements help remove contaminants and particles that enter the respiratory tract up the hariku.

4. Maintaining Optimal pH: Mucosa secreted by epithelial nests of Brunn also contains buffer systems that help maintain optimal pH in the respiratory tract. This is important for the normal functioning of various enzymes and the protection of the mucous membrane from acidic or alkaline substances.

In some cases, such as chronic obstructive pulmonary disease, Brunn's epithelial nests may become hypertrophied (enlarged) and hyperproductive. This can lead to increased mucus production and breathing problems.

In conclusion, Brunn's epithelial nests are an important component of the respiratory system, serving the functions of humidification, protection and clearance of the airways. Their work is aimed at maintaining optimal conditions inside the lungs and protecting the body from harmful substances and infections. Understanding the role of Brunn's epithelial nests is an important aspect in the study of the respiratory system and its functioning. Further research in this area will allow us to better understand the mechanisms of these nests and their impact on human health.