Growth Hormone (Gh), Somatotropic Hormone (Somatotrophin)

Growth Hormone (Gh), Somatotropic Hormone (Somatotrophin) is one of the most important hormones in our body. It is synthesized in the anterior lobe of the pituitary gland, a gland located in the brain. Responsibility for its production lies with the hypothalamus, the part of the brain that regulates the functioning of the pituitary gland.

Growth hormone performs several important functions in the human body. It stimulates the growth of long (tubular) bones of the limbs, which is especially important in childhood and adolescence. In addition, this hormone increases the formation of protein in the body due to its effect on somatomedins, special proteins produced by the liver.

Control of the synthesis and release of growth hormone in the body is carried out by the releasing hormone - releasing factor, produced in the hypothalamus, as well as somatostatin - a hormone that is produced in another part of the pituitary gland and which can reduce the release of growth hormone.

Excessive production of growth hormone in humans can lead to gigantism before puberty and acromegaly in adults. Gigantism is a disease in which a person begins to grow beyond normal due to excessive secretion of growth hormone at a young age. Acromegaly is a disease that develops in adults whose blood levels of growth hormone are high for a long time. This leads to an increase in bone size, increased blood sugar levels, and disruption of the functioning of some internal organs.

Lack of growth hormone in the body of children leads to dwarfism. This disease is characterized by delayed growth and development, which can lead to serious health problems.

Taking all of the above to a practical level, we can say that growth hormone is a key factor in the growth and development of the body. Its deficiency or excess can lead to serious disorders, so it is very important to monitor its level in the body. If you notice any abnormalities in your child's growth or development, you should consult a doctor for diagnosis and treatment.

Growth hormone (GH), also called growth hormone (GH), is a hormone produced by the anterior pituitary gland. It stimulates the growth of long tubular bones of the limbs, and also increases protein synthesis in the body through somatomedin.

The synthesis and release of growth hormone is controlled by growth hormone releasing hormone, which is produced in the hypothalamus, as well as somatostatin.

Excessive production of growth hormone in childhood leads to gigantism, and in adults to acromegaly. Insufficient production of growth hormone in children causes dwarfism.

Growth hormone, also known as growth hormone, is an important regulator of growth and development in the human body. It is synthesized in the anterior pituitary gland, a gland located at the base of the brain. Growth hormone plays a critical role in stimulating the growth of the long bones of the limbs, such as the spine, hips and legs. In addition, it influences protein formation in the body through a substance called somatomedin.

The synthesis and secretion of growth hormone are controlled by a complex system. Growth-hormone releasing hormone, produced in the hypothalamus, stimulates the production and release of growth hormone in the anterior pituitary gland. On the other hand, somatostatin, which is also produced in the hypothalamus, reduces the production of growth hormone.

Growth hormone has an important effect on the growth and development of the body. In childhood, its deficiency can lead to slow growth and dwarfism. This condition is known as hypopituitary dwarfism. Growth hormone deficiency can be caused by a variety of reasons, including genetic abnormalities or damage to the pituitary gland.

On the other hand, excess production of growth hormone in the human body can lead to two different conditions: gigantism and acromegaly. Gigantism occurs when excess growth hormone is present before puberty. This causes a disproportionate increase in height and limb length, which can lead to serious medical problems. Acromegaly, on the other hand, develops when excess growth hormone is present in adults. In this case, the growth of the limbs has already been completed, so acromegaly manifests itself in an increase in the size of soft tissues and internal organs, which can also cause serious complications.

Treatment of conditions associated with excess or insufficient production of growth hormone may include various methods. In cases of growth hormone deficiency in children, replacement therapy with synthetic growth hormone is usually used to stimulate normal growth and development. If growth hormone is overproduced, surgery, drug therapy, or radiation may be used to control the secretion of the hormone and reduce its levels in the body.

In conclusion, growth hormone (Gh) or somatotropic hormone (GH) plays an important role in regulating the growth and development of the body. It stimulates the growth of long bones and increased protein formation. Too little or too much growth hormone can cause serious medical conditions such as childhood dwarfism, gigantism, and acromegaly. Treatment of these conditions is based on normalizing the level of growth hormone in the body, which may include replacement therapy or other methods aimed at regulating its secretion.