Guaffona-Ru Method

The Guaffona Roux Method is a method for studying the properties of drugs that was developed by the French pharmacist Rene Goffin in the 19th century. This method is based on the use of plant extracts and other natural components to treat various diseases.

Guaffona Roux The method involves several steps, including preparing the plant material, extracting the active substances and performing various tests to determine their properties. For example, this method can be used to determine the antimicrobial activity of plant extracts or to study their effect on blood pressure.

One of the main advantages of Guaffon Ru Method is its safety for patients, since it does not contain synthetic components and does not cause side effects. In addition, this method allows you to study the properties of plant extracts without the need to conduct expensive experiments on animals.

However, the Guaffona Roux Method is not always effective for treating serious diseases such as cancer or HIV. Therefore, to treat such diseases, more complex methods based on the synthesis of new drugs are used.

Overall, the Guaffona Roux Method is an important tool for studying the properties of plant extracts, but cannot be used as a sole treatment method.

**Guaffona-Ru method**

This method is referred to as the modified Goufflon method. It was discovered in the 20s of the last century by the French pharmacist R. Goiffon, but in the same period it received the greatest development thanks to the French pharmacologist R. Roux. Based on the Guaffon-Ru method, various modifications have been created such as HCH (hexachlorocyclopentadiene) - a drug from the group of highly toxic drugs. It is used for processing agricultural crops, but in humans it causes damage to the liver, central nervous system, bone marrow and blood, leads to disruption of the reproductive function of a woman’s body, and significantly disrupts spermatogenesis and sperm statistics of a man. In experimental studies, it was noted that aerosol particles of HCH penetrate into the epidermal tissue and through it enter the systemic bloodstream. It is possible that they are capable of being absorbed by the vascular endothelium as they pass through the dermis of the skin. Part of the drug entering the bloodstream is unchanged, and can also be captured by hepatocytes under the influence of the liver mononuclear phagocyte system. When the drug HCCD is administered to mice in large doses, high sensitivity and rapid death of experimental animals from toxicosis are observed. Guaffona and Roux's method is sometimes considered too troublesome. Although the method is used quite rarely, it should be borne in mind that with this method the suspended reaction product