Hemoglobin Abnormal

Hemoglobin is a protein found in red blood cells and is responsible for transporting oxygen in the body. Hemoglobin is made up of four protein chains that form a tetramer called globin. Hemoglobin may be normal or abnormal depending on the structure of the globin chains.

Abnormal hemoglobin, or hemoglobin associated with hereditary disorders of the primary structure of the globin chain, can lead to the development of hemolytic anemia (destruction of red blood cells). Hemolytic anemia can be caused by a variety of causes, including genetic disorders, infections, autoimmune diseases, and other factors.

In inherited disorders of the primary structure of globin, some globin chains may be altered or missing, resulting in the formation of abnormal hemoglobin. This hemoglobin may be less efficient at transporting oxygen, which can lead to decreased oxygen levels in the blood and impaired function of organs such as the heart and lungs.

The presence of abnormal hemoglobin can be detected through a blood test that determines the level of hemoglobin and its forms. Treatment for hemolytic anemia may include red blood cell transfusions, hemoglobin replacement, or medications that can help restore normal globin chain structure.

Thus, abnormal hemoglobin can be caused by hereditary disorders of the globin chain structure and lead to the development of hemolytic anemia. Diagnosis and treatment of this pathology require careful examination and timely intervention.

Hemoglobin abnormality

Abnormal (dystrophic) hemoglobin is a form of hemoglobin that has a disturbed structure and can lead to various diseases. With this quality, there is a lack of oxygen carrier in the blood, which has a bad effect on a person’s well-being.

The mechanism of appearance of Hemoglobin abnormality

Some studies suggest that the abnormal shape of the hemoglobin molecule results from mutations in the HBA2 gene. Mutations in this gene can affect the quality of hemoglobin and lead to its abnormal state. As a result of mutations, the structure of this protein in some