Hemoglobin Unstable

Hemoglobin is an iron-containing protein that is part of red blood cells. Hemoglobin performs many functions in the body. One of them is the transport of oxygen from the lungs to the tissues and carbon dioxide in the opposite direction. Thanks to hemoglobin, oxygen saturation occurs and carbon dioxide is removed.

Hemoglobin can be stable or unstable. Hemoglobin A is the most stable of all types of hemoglobin, making it ideal for transporting oxygen throughout the body. However, there are other types of hemoglobin that may be less resistant to various factors.

One of these factors is high temperature. If the ambient temperature is too high, hemoglobin may become unstable and lose its ability to carry oxygen. This can lead to various diseases such as anemia, hypoxia and others.

Another factor that can affect hemoglobin stability is the oxidizing agent. Oxidants are substances that can damage cells and tissues of the body. If oxidizing agents are present in the blood, they can damage hemoglobin and lead to its instability.

There are also many other factors that can affect hemoglobin stability. For example, certain medications, radiation, toxins, and other substances can change the structure of hemoglobin and cause it to become unstable.

Unstable hemoglobin is the general name for abnormal γ-chains of human hemoproteins, characterized by reduced resistance to dehydration, high temperatures and the action of reagents compared to γ-chromoprotein; one of the diagnostic parameters for anemia of various origins. The heterozygous form (hemoglobins F2, G), found in 0.05-0.5% of Caucasians, is characterized by a disruption of the relationship between the intratyrosine pair of the beta chain, which reduces binding to oxygen in general by 20-25%. Hemoglobins S and C also demonstrate an intermediate type of hemolytic instability between the α- and β-chains of hemoglobin A. The reduced affinity of abnormal hemoproteins for tissue oxygenases with preserved mye'' loglobin dihedrocarone chain, detected when analyzing their kinetic characteristics, is traditionally characterized as the “Hilt phenomenon”.