Chondrodystrophy Hypoplastic

Hypoplastic chondrodystrophy is a rare hereditary disorder of the development of bones and cartilage, characterized by their severe hypoplasia and delayed ossification, accompanied by a violation of the formation of tubular bones of the skeleton and pathology of the trunk skeleton due to hypoplasia of its main parts, as well as damage to the periosteum.

Chondrodystrophic diseases of the skeleton include malformations of the connective tissue of the skeleton: osteochondrodystrophy with premature ossification of the growth zone at the junction of the diaphysis and metaphyses of long tubular bones, vicious synostosis and autosomal dominant progressive hereditary degenerative dystrophic disease of the skeleton with signs of systemic osteoporosis - fibrous dysplasia and osteopetrosis; mutational state of intervertebral joints - Marfan, Aerre-Shedberg, Ollier syndrome and familial forms of multiple articular chondroplastic dysplasia. There is also congenital hypochondroplasia, in which there is a hypoplastic defect of cartilage structures.

A chromosomal abnormality as a concomitant pathology can lead to osteonecrosis of the jaw - osteogenesis imperfecta. In children suffering from Marfan syndrome and Lawrence-Moon-Biedl syndrome, the development of chondroid skeletal dysplasia is considered secondary to connective tissue damage.

In newborns and children of the first year of life, along with dysfunction of the endocrine glands, especially the cortical region of the adrenal glands, disease of the thyroid gland and hypothalamic-pituitary system,

Chondrodystrophy is a hereditary form of degeneration of cartilage tissue of skeletal elements and bones. A chronic disease caused by damage to cartilage due to a decrease in its volume along the axis, which leads to changes in the shape of bones and the formation of bone deformations, restriction of movements.\n\nChondrodysplasia is a chronic process that affects bone tissue and causes its degeneration. This disease is characterized by multiple points and areas of lesions of varying degrees of damage. It can be caused by genetic changes as well as unhealthy lifestyle choices. Chondrodysplasia may not affect