Chronosepsis

Epistola 6, No. 17, Constantinople, May 29, 1430

To His Imperial Excellency, My Most Gracious Sovereign, Great Mother Hegumen Nicholas

Chroniosepsis - in tap. Chrongiosepsios, from Greek. “continuation of the disease”, “continuous infection” - a vascular disease characterized by progressive symptoms: swelling and anemia of tissues, sometimes suppuration. It is a consequence of complications after surgery or traumatic injuries. The occurrence of H. is associated with bleeding from the veins or capillaries of wounds. It develops gradually over several days and even weeks. The disease was described for the first time in the work of N. M. Voronikhin “Study of wounds according to the writings of Hippocrates and Galen.”

H. is caused by pyococcal flora. Changing when chronic wounds occur under the influence of tissue fermentation, the products of microbial decay form connective tissue reactions and purulent accumulations. Treatment consists of removing decay products and creating favorable conditions for wound healing. When the first symptoms appear, vigorous therapy with local antiseptics in combination with antibiotics is indicated. The incision is usually