In Ibuta

Country of origin: Germany

Pharm-Group: Anti-inflammatory drugs - propionic acid derivatives

Manufacturers: Tad Pharmaceuticals Wekr GmbH (Germany)

International name: Ibuprofen

Synonyms: Apo-Ibuprofen, Bartel drugs ibuprofen, Bolinet, Bolinet Lingval, Bonifen, Bren, Brufen, Brufen retard, Burana, Dolgit, Dolgit cream, Ibalgin, Ibupron, Ibuprof, Ibuprofen, Ibuprofen Lannacher, Ibuprofen Nycomed, Ibuprofen-Akos, Ibuprofen -Teva, Ibuprofen-Hemo

Dosage forms: film-coated tablets 200 mg, film-coated tablets 400 mg, film-coated tablets 600 mg, film tablets

Ingredients: Active substance - Ibuprofen.

Indications for use: Rheumatoid arthritis, reactive synovitis with deforming osteoarthritis, psoriatic arthritis, acute joint attack with gout, ankylosing spondylitis (Bechterew's disease), cervical spondylosis, Barre-Lieu syndrome (cervical migraine, vertebral artery syndrome), lumbodynia, sciatica, thoracic radicular syndrome, bursitis, tendovaginitis, myalgia, neuralgic amyotrophy, occipital and intercostal neuralgia, sprains of the ligamentous apparatus, hematomas, injuries, pain in the area of ​​the surgical wound, toothache, surgical operations in the oral cavity, panniculitis, tonsillitis, pharyngitis, laryngitis, sinusitis, rhinitis, bronchitis, pneumonia, inflammatory processes in the pelvis, disalgomenorrhea, colds, ARVI, febrile conditions, postural hypotension when taking antihypertensive drugs, nephrotic syndrome (to reduce the severity of proteinuria).

Contraindications: Hypersensitivity, peptic ulcer of the stomach and duodenum in the acute phase, nonspecific ulcerative colitis, aspirin-induced asthma, leukopenia, thrombocytopenia, hemorrhagic diathesis, severe dysfunction of the liver and kidneys, portal hypertension, arterial hypertension, heart failure, diseases of the optic nerve, scotoma, amblyopia, color vision impairment, pregnancy, breastfeeding.

Side effects: Dyspeptic disorders (nausea, heartburn, anorexia, vomiting, discomfort in the epigastric region, flatulence, diarrhea, constipation), erosive and ulcerative lesions of the gastrointestinal tract with signs of gastrointestinal bleeding, headache, dizziness, tinnitus, insomnia, agitation , visual disturbances (blurred vision, changes in color vision), fluid retention, edema, increased blood pressure, thrombocytopenia, granulocytopenia, hemolytic anemia, Quincke's edema, broncho-obstructive syndrome, skin allergic reactions.

Interaction: Reduces the antihypertensive activity of ACE inhibitors, the natriuretic activity of furosemide and hypothiazide. May increase the toxicity of methotrexate and lithium preparations. When combined with coumarin-type anticoagulants and alcohol, it increases the risk of hemorrhagic complications, and with tableted glucocorticoids - the risk of gastrointestinal bleeding.

Overdose: Symptoms: abdominal pain, nausea, vomiting, lethargy, drowsiness, depression, headache, tinnitus, metabolic acidosis, coma, acute renal failure, hypotension, bradycardia, tachycardia, atrial fibrillation and respiratory arrest.

Special instructions:

1. Prescribe with caution to elderly people, with diseases of the gastrointestinal tract, liver and kidneys.
2. If side effects occur, discontinue or reduce the dose.
3. Avoid simultaneous use with other NSAIDs, anticoagulants and alcohol.
4. Monitor liver and kidney function during long-term use.
5. Drinking alcohol is not recommended.

Literature: Encyclopedia of Medicines, 2004.