Jacobsona Symptom

Jacobson's symptom is a symptom described by the German physician P. Jacobson. It is characterized by the appearance of pain in the calf muscles when palpated in a state of maximum tension.

This symptom occurs with kidney diseases, in particular with glomerulonephritis. It is believed that the cause of pain is the increased content of nitrogen metabolism products (urea, creatinine, etc.) in the blood. These substances irritate the nerve endings in the muscles, causing pain.

Therefore, the appearance of pain in the calf muscles during palpation can serve as an important diagnostic sign of kidney disease, accompanied by impaired excretion of nitrogenous waste. The symptom is named after its discoverer, the German doctor P. Jacobson.