Ketanest

Ketanest: description, indications and contraindications

Ketanest is a non-inhalation anesthetic drug belonging to the group of non-barbiturates. It is produced in Germany by the companies Goedecke and Parke-Davies and has the international name "Ketamine". In addition, the drug is known under the synonyms “Calipsol”, “Ketalar”, “Ketamine hydrochloride”.

Ketanest is available in the form of an injection solution, the active ingredient of which is Ketamine.

Indications for the use of Ketanest include induction anesthesia, basic anesthesia for pain relief for short-term operations and painful instrumental interventions. The drug can also be used in dental, ophthalmological, otorhinolaryngological, gynecological and obstetric practice, as well as in diagnostic procedures such as endoscopy, cardiac catheterization and others.

In addition, Ketanest can be used during emergency surgical operations in patients with traumatic shock and blood loss, as well as for pain relief during transportation of patients and treatment of burn surfaces.

Despite the wide range of indications, the drug also has contraindications. Ketanest is not recommended for cerebrovascular accidents, arterial hypertension, preeclampsia, eclampsia, alcoholism, and epilepsy in children. In addition, there are restrictions on the use of the drug for kidney diseases, angina pectoris, decompensated heart failure, as well as for operations on the larynx and pharynx.

Ketanest can cause a number of side effects, including increased blood pressure, tachycardia, drooling, nausea, shortness of breath, depression of the respiratory center, muscle rigidity and increased muscle activity, obstruction of the upper respiratory tract due to spasm of the masticatory muscles and retraction of the tongue. During the period of recovery from the state of anesthesia, hallucinations, psychomotor agitation, prolonged disorientation, and psychosis may occur. Pain and hyperemia may also be observed along the vein at the injection site.

The interaction of Ketanest with other drugs can enhance the effect of inhalation anesthetics, as well as deepen muscle relaxation caused by tubocurarine and ditilin. However, the drug does not change the effect of pancuronium and succinylcholine. Patients taking iodine-containing drugs may have an increased risk of developing thyrotoxicosis.

In general, Ketanest is an effective means for non-inhalation anesthesia, but its use should only be carried out by an anesthesiologist in strict accordance with the indications and contraindications. In addition, precautions must be taken when using the drug, such as dosage control and monitoring of important indicators of the patient's body.