Atrophic hand Aran-Duchenne hand is a severe congenital hereditary disease of the hands, which is characterized by atrophy of the fingers, neck and chest. The disease is the result of a mutation in the AR gene on one of the chromosomes. Atrophatic Arabic brush is usually observed in men or twins. Genetic testing determines a person's likelihood of developing such a disease. People with Eruc's disease die in infancy or begin to suffer between the ages of 3 and 5 years. The disease leads to serious problems in the human hands and musculoskeletal system. Echocardiography and genetic studies are used to diagnose the disease. Treatment consists of insulin implantation and uses diet changes and medications. Surgical methods can also be used to treat the disease. Over time, the presence of hand atrophy becomes more obvious. Atrophic syndromes can be eliminated by using special devices that help move the fingers. Doctors usually prescribe various procedures to slow down the atrophy process. The study of such diseases not only provides a deeper understanding of such pathologies, but also provides important information regarding family planning and the prevention of possible hereditary changes.