Paget cells

Hello! Today I would like to talk about Paget cells, which are an important component of our skin and play a role in protecting against infections and other diseases. The cells are found on the surface of hair follicles and are responsible for producing sebum, which protects our skin from harmful bacteria and fungi. However, in some cases, Paget cells can become a source of tumors or skin diseases such as psoriasis, eczema and others. These conditions may manifest as changes in skin color, peeling, or even bleeding.

What are Paget's cells? The cells were named after a German dermatologist named Paget, who described them in 1847. He first noticed their appearance during the treatment of psoriasis. Paget's cells are round or oval formations no larger than 30-40 microns in size, having a convex surface and stained with any basic dye - no acid formation reaction occurs. The main function of Paget cells is the production of sebum. It keeps the skin soft and elastic and protects it from infections. In addition, Paget cells are involved in hair formation, providing necessary skin lubrication.

Why might Paget's cells be a problem? Pedjed cells often cause the development of certain skin diseases. For example, the paratumor form of xeroderma pigmentosum (common in infants). The tumor-like variety may be accompanied by flat, small-nodular rashes of yellowish-gray or brown color with some positive Nikolsky's sign. The following forms of developmental defects of Page cells on the facial skin are distinguished: epidermotropic (applies to the superficial layers of the epidermis); epidermoepithelio