Lactulose

Lactulose: an effective remedy for the treatment of constipation and other intestinal diseases

Lactulose is a synthetic laxative that is widely used to treat constipation and other bowel conditions. The drug is produced by Ipico in Egypt and has the international name Lactulose. It is also known by such synonyms as Duphalac, Lactulose Poly, Lactulose syrup, Livo-lac, Normaze, Portalac and Portalac.

Lactulose is produced in the form of syrup and contains the active substance - lactulose. It works by increasing the number of beneficial bacteria in the intestines and reducing the levels of toxins that can cause constipation and other problems.

Indications for the use of Lactulose include constipation (including chronic), hepatic encephalopathy, including coma and precoma, disturbance of intestinal flora (including salmonellosis, shigellosis and other infections), putrefactive dyspepsia syndrome in young children, pain syndrome after removal of hemorrhoids nodes

However, like any other drug, Lactulose has its contraindications and side effects. It should not be used for hypersensitivity, galactosemia and intestinal obstruction. Side effects may include flatulence, diarrhea, cramping, nausea, vomiting, discomfort, and loss of electrolytes.

It is also important to consider the possible interaction of Lactulose with other drugs. For example, antibiotics (such as neomycin) and non-absorbable antacids may reduce its effectiveness. It is recommended not to take Lactulose within 2 hours of taking other medications.

Lactulose should be used with caution in patients with diabetes mellitus (especially in the treatment of hepatic encephalopathy) and with lactose intolerance. If diarrhea occurs, treatment should be stopped. For gastrocardial syndrome, doses should be gradually increased to avoid flatulence. Usually, flatulence disappears on its own after 2-3 days of treatment. Lactulose should not be prescribed against the background of abdominal pain, nausea and vomiting. During long-term treatment (more than 6 months) with high doses, the level of electrolytes in the blood should be regularly monitored.

The dosage of Lactulose depends on the age and condition of the patient, as well as the nature of the disease. Usually the drug is taken 1-2 times a day, 15-30 ml of syrup diluted in 100-200 ml of water. The dose can be increased as needed, but not more than 45 ml per day.

In the treatment of hepatic encephalopathy, Lactulose is taken in large doses (up to 60 ml 3-4 times a day) until soft stools are achieved. Then the dose can be reduced to maintenance (15-45 ml per day).

Overall, Lactulose is an effective and safe drug for the treatment of constipation and other intestinal diseases. However, before using it, you should consult your doctor to make sure it is necessary and safe in your particular case.