Lipodystrophy

Lipodystrophy is a group of rare diseases characterized by the abnormal distribution of fat tissue in the body.

In lipodystrophy, there is a progressive loss of subcutaneous fat (lipoatrophy) in some areas of the body, while in other areas there is excess fat deposition (lipohypertrophy). Most often, fat atrophy affects the limbs and buttocks, and hypertrophy affects the abdomen, neck, and face.

The causes of lipodystrophy are not completely clear. It is believed that both genetic factors and exposure to external factors (viral infections, toxins, injuries, drugs) play a role in its development.

The main symptoms of lipodystrophy include: thinning of subcutaneous fat in certain areas, increased fat deposition in other areas, muscle weakness, diabetes, elevated triglyceride levels.

Diagnosis is based on analysis of the clinical picture and data from imaging methods (MRI, CT). Treatment includes correction of metabolic disorders and plastic surgery to restore a normal body profile. The prognosis depends on the form and severity of the disease.

**Lipodystrophy** is a lesion of adipose tissue, characterized by various changes up to complete disappearance. The various forms are based on metabolic disorders, less often on degenerative processes. Thus, the sclerosing variety of lice is caused by insufficient blood supply and trophic stimulation of the skin, followed by sclerosis of fatty tissue in the absence or extreme insufficiency of the function of the sebaceous glands [1]. With this form of L., the skin is dense, lacks turgor and elasticity, its color is grayish-white, sometimes with a yellowish tint, lichenified, sometimes atrophic, subcutaneous fat is atrophied, up to severe cachexia. This is a pronounced local process, usually involving the skin and subcutaneous fatty tissue of the face and neck, with subsequent damage to the sebaceous gland and hair follicle. Localization is typical