Mouse Hepatitis Virus

The mouse hepatitis virus belongs to the genus coronaviruses. It causes liver disease (hepatitis) in mice.

This virus was first identified in the 1980s in laboratory mice with signs of hepatitis. When infected, the virus multiplies in the liver, leading to inflammation and necrosis of liver cells.

In mice, the disease is usually acute and fatal. The virus is transmitted by the fecal-oral route and is highly contagious among colonies of laboratory mice.

The pathogenicity of this virus for humans has not yet been established. More research is needed to study the possibility of human infection and disease development. There are no reports of human cases of murine hepatitis virus yet. However, precautions are recommended when working with infected laboratory animals.



The mouse hepatitis virus belongs to the genus coronaviruses. It causes liver disease in mice, but its pathogenicity in humans has not yet been established.

This virus was first isolated in 1978 from the liver of laboratory mice with signs of hepatitis. By electron microscopy, the virus particles had a morphology typical of coronaviruses - crown-like outgrowths on the surface of the virion.

Murine hepatitis virus causes acute liver inflammation in newborn and adult mice. The disease is characterized by increased activity of liver enzymes in the blood and necrosis of hepatocytes. The virus is found in the liver, feces and urine of infected mice.

Despite the ability of this virus to infect mouse liver cells, its pathogenic properties in relation to humans have not yet been confirmed. More research is needed to determine whether murine hepatitis virus can cause human infection and liver disease.