Nephrosclerosis

Nephrosclerosis is a pathological condition that is associated with the gradual replacement of functional kidney tissue with connective (scar) tissue. It is characterized by an increase in kidney mass due to the proliferation of connective tissue, the development of arteriosclerosis, a decrease in the volume of the renal parenchyma and subsequent damage to the nephron. The consequence of this is a decrease in kidney function and disruption of homeostasis.

Risk factors for the development of nephrosclerotic changes include arterial hypertension, chronic kidney disease in childhood, diabetes mellitus, age over 50 years, male gender, family history, and other factors that may increase the risk of nephropathy. At the same time, the presence and rate of development of nephropathy is influenced by genetic factors. In this article we will talk about the causes and mechanism of development of nephroskerosis and ways to prevent it.

Nephroscopy (also known as kidney biopsy