Peptonuria

Peptonuria is the presence in the urine of peptones - intermediate compounds formed during the digestion of proteins.

Peptones are formed in the stomach and small intestine when proteins are broken down by digestive enzymes. Normally, peptones are absorbed into the blood and are then used by the body to build its own proteins.

With peptonuria, the reabsorption of peptones in the renal tubules is impaired, resulting in their release into the urine. This can be caused by damage to the renal epithelium due to various diseases or intoxications.

Diagnosis of peptonuria is based on the detection of peptones in urine using qualitative or quantitative methods.

Treatment is aimed at eliminating the underlying disease that caused the malabsorption of peptones. The prognosis depends on the severity and nature of the underlying pathological process.



Peptonuria is a condition characterized by the presence of peptones in the urine.

Peptones are intermediate products of protein breakdown during digestion. Typically, peptones are completely absorbed in the intestine and do not pass into the urine.

The causes of peptonuria may be:

  1. Damage to the mucous membrane of the small intestine due to diseases such as enteritis, celiac disease, etc. This leads to impaired absorption of peptones.

  2. Increased permeability of renal tubules in kidney pathologies.

  3. Excessive formation of peptones in the small intestine due to increased breakdown of proteins.

Diagnosis of peptonuria is based on the detection of peptones in urine using qualitative or quantitative methods.

Treatment is aimed at eliminating the underlying disease that caused the condition. The prognosis depends on the effectiveness of therapy.



Peptonuria is a rare disease in which substances associated with the digestion of proteins appear in the urine. This condition can be caused by various reasons, including problems with the kidneys, liver, pancreas and other organs.

Peptones are intermediate compounds formed during the digestion of proteins in the gastrointestinal tract. They are a mixture of various amino acids and other substances that are formed as a result of the hydrolysis of proteins. With peptonuria, these compounds enter the urine, which leads to changes in it.

Symptoms of peptonuria may include changes in urine color, odor, and clarity. You may also experience abdominal pain, nausea, vomiting and other symptoms associated with disruption of the gastrointestinal tract.

The causes of peptonuria can be different. The most common are diseases of the kidneys, liver and pancreas, as well as metabolic disorders. Peptonuria can also be caused by taking certain medications or toxic substances.

Diagnosis of peptonuria is based on a urine test. It may contain peptones and other substances associated with digestion. Additional research is also being carried out to determine the cause of the disease.

Treatment for peptonuria depends on its cause. If the disease is caused by problems with the kidneys or liver, then treatment of these organs may be required. If peptonuria is caused by other causes, then treatment may include medications, lifestyle changes and other methods.

In general, peptonuria is a serious disease that requires timely diagnosis and treatment. If you notice changes in your urine or other symptoms of peptonuria, contact your doctor for advice and further treatment.



**Peptonuria** (also Peptonuria, Peptonurie) is a condition in which the presence of peptides and their breakdown products - pentones - is detected in the urine. This type of disorder is the result of an illness or disease that causes a buildup of protein in the blood. The mechanism for the appearance of pentones in urine is associated with the breakdown of proteins into smaller compounds and molecules, which are then excreted by the kidneys through the bladder.

With peptonuria, a picture of frequent urination occurs in combination with reddish-brown discharge, which indicates the presence of penton - products of protein decomposition, such as hemoglobin and myoglobin proteins, beta and gamma kappapeptides, urocarboxymethylcaptapeptide and other products. In the presence of protein metabolites, more complex molecules can be detected. This disease has symptoms of intoxication, as well as renal failure and dystrophy of the genitourinary system in some patients with this disease.

The appearance of pentones in urine can be caused by various reasons. Harmful factors and abnormalities in kidney function can cause the formation of pentons even in healthy people. Bacteria that act on the products of protein metabolism (e.g., proteolytic bacteria are a common factor) can promote the breakdown of proteins and the formation of peptides. Sometimes the cause may be accelerated protein metabolism, for example, after training or prolonged stress. Often this is also caused by inflammatory diseases of the genitourinary area and intestines, tumors and infections of various kinds, hepatitis, and cirrhosis of the liver.

Another reason for the development of this disease is the lack of digestive enzymes responsible for the breakdown of proteins in the body. Diseases of the pancreas or disruption of the absorption of nutrients in the intestine also contribute to the appearance of pentons in the secretions. Acute and chronic bowel diseases can affect nutrient absorption and the production of digestive enzymes. Enzyme deficiency affects the breakdown of food and the process of processing it into proteins. This circumstance leads to their accumulation in the blood and organs, which causes the formation of foam or peptones. Lack of vitamin D also affects protein metabolism, hence the presence of penitations in the urine.