Progestogens

Progestogens are hormonal drugs that belong to the group of gestagens. Progestogens imitate the action of the hormone progesterone, which is produced in the ovaries in the second phase of the menstrual cycle.

Progestogens are used in medicine for various purposes:

1. As part of combined oral contraceptives to prevent unwanted pregnancy. Progestogens in these drugs suppress ovulation and create unfavorable conditions for fertilization and implantation of the egg.

2. For hormonal therapy in perimenopause to eliminate the symptoms of menopausal syndrome.

3. As part of hormonal drugs for the treatment of endometriosis, uterine fibroids and other gynecological diseases associated with hormonal imbalance.

4. To support the luteal phase during in vitro fertilization.

The most well-known progestogens are pregnene derivatives (progesterone, dydrogesterone), 19-nortestosterone derivatives (norethisterone, norethindrone), spironolactone derivatives (drospirenone). The choice of a specific drug depends on the indications and preferences of the doctor.