Secretin (Secrelin)

Secretin: a hormone that regulates digestion

Secretin is a hormone that plays an important role in digestion. It is produced in the small intestine when acidic chyme from the stomach enters the duodenum. Secretin stimulates the secretion of alkaline juice in the pancreas and bile in the liver, which helps neutralize the acidity of the food bolus and improves digestion.

Secretin was discovered in 1902 by Jena University scientist Ernst Starling and his colleague William Bailey Jackson. They found that injection of small intestinal extract in dogs caused the secretion of bile and alkaline juice in the pancreas.

Secretin is a polypeptide hormone consisting of 27 amino acids. It is produced in enterocretin cells, which are located in the mucous membrane of the duodenum. Secretin is released into the bloodstream and reaches the pancreas and liver, where it stimulates the production of alkaline juice and bile, respectively.

Secretin also plays a role in regulating the acidity of stomach contents. When an acidic food bolus enters the duodenum, secretin stimulates the secretion of alkaline juice in the pancreas. This helps neutralize the acidity of food and prevents damage to the intestinal lining.

In addition, secretin slows down the peristalsis of the stomach and colon. This helps increase the time the food bolus spends in the stomach and intestines, which promotes more complete and efficient digestion.

In conclusion, secretin is an important hormone that plays a key role in regulating digestion. It stimulates the production of alkaline juice and bile, helps neutralize the acidity of food and improves the digestive process in general.



Secretin is a hormone that is released in the duodenum when acidic chyme passes from the stomach into the intestines. It plays an important role in the regulation of digestion, as it stimulates the secretion of the pancreas and bile.

Secretin is one of the hormones that regulate the functioning of the gastrointestinal tract. It is produced in the duodenum and is involved in the digestion process. When acidic chyme enters the duodenum from the stomach, secretin begins to be released.

This hormone has several functions. Firstly, it stimulates the secretion of alkaline juice by the pancreas. Alkaline juice is necessary for the breakdown of proteins, fats and carbohydrates. In addition, secretin also stimulates the liver to secrete bile, which is necessary for the digestion of fats.

However, secretin not only regulates the digestion process. It also plays an important role in controlling peristalsis, which is the movement of food through the gastrointestinal tract. Secretin can slow down intestinal motility, which helps food be better absorbed.

Thus, secretin is an important hormone that is involved in the regulation of the gastrointestinal tract and ensures proper digestion.



Secretin is a hormone that is produced in the duodenum and stimulates the production of bile and pancreatic juice. It also slows down the peristalsis of the intestines and stomach.

The main effect of secretin is to stimulate the production of bile, which is necessary for the digestion of fats. Secretin also stimulates the production of pancreatic enzymes that break down carbohydrates and proteins.

In addition, secretin plays an important role in regulating blood sugar levels by stimulating the production of insulin and glucagon. Insulin lowers blood glucose levels, while glucagon, on the contrary, increases it.

A lack of secretin can lead to digestive disorders and various diseases such as diabetes, obesity and others. Therefore, it is important to maintain normal levels of secretin in the body.