Slow Repolarization Phase

The slow repolarization phase is one of the phases of the cardiac cycle. It follows the phase of rapid repolarization and precedes diastole.

During the slow repolarization phase, a gradual restoration of the resting potential of cardiomyocytes occurs. This occurs due to the exit of potassium ions from the cell and the entry of sodium ions. Thus, the membrane potential of cardiomyocytes gradually returns to its original negative value.

The duration of the slow repolarization phase is approximately 150 ms. It ensures complete restoration of cardiomyocyte excitability before the next heart contraction. Disturbances in repolarization processes can lead to various cardiac arrhythmias.

Thus, the slow repolarization phase plays an important role in ensuring normal heart rhythm. It allows myocardial cells to return to their original state and prepare for the next cycle of excitation.

The slow repolarization phase (SRP) is a stage of depolarization of the cell membrane that occurs between the fast repolarization and fast depolarization phases. This phase is also called the slow depolarization stage or the stationary stage. FMR is one of the three main states of the cell membrane, along with rapid repolarization and rapid depolarization.

According to the mechanism of its occurrence, the slow repolarization phase resembles a cellular resting state; it is also similar to neurotransmitters and has properties similar to passive electric current. Thus, FMR can be understood as a complex structure that includes all the processes that determine the time required for excitation and, consequently, the time the cell responds to an external stimulus.