Metanephrogenic tissue

Metanephrogenic tissue is tissue that is formed in the kidneys of humans and animals. It is derived from metanephron - a hormonal cell that secretes erythropoietin, which regulates erythropoiesis - the process of formation of red blood cells.

The metanephrogenic epithelium consists of two types of cells: proximal and distal nephrons. The proximal nephrons are responsible for filtering blood and producing urine, while the distal nephrons are responsible for the secretion of hormones such as renin, erythropoietin and prostaglandins.

The process of formation of metanephrogenic tissue begins in the early stages of embryonic development of the kidney. Several factors are involved in this process, including the FGF10 gene, which stimulates the growth and differentiation of metanephrogenic cells.

An important property of metanephrogenic epithelium is its ability to regenerate. Once metanephrons are damaged or removed, they can regenerate and restore their function. This property could be used to develop new treatments for kidney diseases such as kidney failure or cancer.

In general, metanephrogenic tissue plays an important role in maintaining normal kidney function and regulating hormonal balance in the body.

*Metanephrogenic tissue is a unique biological tissue or organ that was discovered and described only recently. It is a complex of cells that perform important functions in the human body.

The development of metanephrogenic tissue is associated with the process of embryogenesis and occurs at a certain stage of intrauterine development. This process is important for the formation of organs of the genitourinary system, such as the kidneys and bladder.

History of discovery and research The discovery of metanephrogenic tissue is associated with experiments conducted by a group of scientists from the National Cancer Institute (NCI) in the USA. They were interested in studying the molecular mechanisms that regulate tissue development. One of the researchers, Michael Bento, became interested in the fact that the development of metanephrotic blastema, that is, abnormal tissue that occurs in various kidney tumors, may be due to the same developmental mode that regulates the development of normal tissue in