Vancocin

s powder for the preparation of an injection solution, lyophilisate for the preparation of a solution for infusion 500 mg

Vancocin (international name Vancomycin) is an antibacterial drug belonging to the group of glycopeptide antibiotics. It is widely used for the treatment of severe infectious and inflammatory diseases caused by pathogens sensitive to vancomycin, such as sepsis, endocarditis, pneumonia, lung abscess, osteomyelitis, infections of the skin and skin structures, pseudomembranous colitis caused by Clostridium difficile, enterocolitis, meningitis.

Vancocin is manufactured by Lilly Pharma Fertigung (Germany), Eli Lilly (United States of America) and Eli Lilly (Germany). The dosage form of Vancocin is powder for the preparation of an injection solution and lyophilisate for the preparation of a solution for infusion of 500 mg. The active substance is vancomycin.

In addition to its primary use, Vancocin can be used to prevent infections in patients with heart failure or heart defects who are undergoing invasive procedures.

When using Vancocin, side effects are possible, such as nausea, vomiting, bitter taste in the mouth, chills, itching, urticaria, Stevens-Johnson syndrome. After IV administration, thrombophlebitis, vasculitis, fever, neutropenia, eosinophilia, thrombocytopenia, and sometimes anaphylactoid reactions may occur. With rapid intravenous administration, a burning sensation, redness of the upper body (red neck syndrome), pain and muscle spasms in the back and chest, arterial hypotension, dizziness, and tinnitus are possible. In rare cases, oto- and nephrotoxic effects are possible (hearing loss up to deafness, renal failure, azotemia, interstitial nephritis).

Vancocin is contraindicated in case of hypersensitivity, acoustic neuritis, pregnancy in the first trimester. Restrictions on use include severe kidney damage, hearing impairment, pregnancy in the second and third trimesters, breastfeeding (breastfeeding should be suspended).

Interaction of Vancocin with other drugs may lead to an increase or decrease in their effect. It is especially important to avoid concomitant use with other antibacterial drugs such as aminoglycosides, as this may lead to an increased risk of intolerance and toxicity.

Before starting treatment with Vancocin, it is necessary to conduct tests for the sensitivity of the pathogen to the antibiotic and take into account recommendations for dosage and duration of treatment. Vancocin is usually used in a hospital setting under the supervision of a physician.

In general, Vancocin is an effective and widely used antibacterial drug, but its use should be limited only as prescribed by a doctor and in accordance with the instructions for use.