Verapamil Hydrochloride

Verapamil hydrochloride: use, action and contraindications

Verapamil hydrochloride is a drug belonging to the group of calcium channel blockers of the phenylalkylamine group. It is widely used in clinical practice for the treatment of various cardiovascular diseases. In this article we will look at the main aspects of using verapamil hydrochloride, its action, contraindications and possible side effects.

Verapamil hydrochloride is produced by several pharmaceutical companies, including Akrikhin KhFK (Russia), Biosynthesis (Russia), Borisov Medical Preparations Plant (Belarus), Bryntsalov (Russia), Veropharm/Belgorod Branch (Russia), Knoll AG (Germany), Mir-Pharm ( Russia), Moskhimfarmpreparaty im. ON THE. Semashko (Russia) and others.

Verapamil hydrochloride has the international name "verapamil" and is also known by various synonyms, including atsupamil, vepamil, veracard, veramil, verapabene, verapamil (Mival), verapamil-MIC, verapamil-Ratiopharm, vero-verapamil, verogalide EP, veromil, danistol, isoptin, isoptin SR, kaveril, lekoptin, falicard, falicard long, etc.

Verapamil hydrochloride is available in various dosage forms, including 0.25% injection solution, substance, 80 mg tablets, and 40 mg and 80 mg film-coated tablets.

The active ingredient in verapamil hydrochloride is verapamil. It exerts its effect by blocking calcium channels in the heart muscles and blood vessels, which leads to vasodilation and a decrease in peripheral vascular resistance, as well as a decrease in the contractile activity of the heart. This helps reduce the load on the heart and improve its blood supply.

Verapamil hydrochloride is used to treat several conditions, including paroxysmal supraventricular tachycardia (except WPW syndrome), sinus tachycardia, atrial premature beats, atrial fibrillation and flutter, angina (including Prinzmetal, tension, post-infarction), hypertension, hypertensive crisis, idiopathic hypertrophic cardiomyopathy etc.

Verapamil hydrochloride has several contraindications and warnings. It should not be used when:

1. Allergies to verapamil or other components of the drug;
2. Sick sinus syndrome (sinus bradycardia, heart block);
3. Very low blood pressure (systolic pressure below 90 mmHg);
4. Very low cardiac output;
5. Very severe heart disease (eg, acute heart failure, shock);
6. Taking ACE inhibitors (angiotensin-converting enzyme) or beta-blockers within the last 48 hours;
7. Pregnancy and breastfeeding (use only as prescribed by a doctor).

Side effects from the use of verapamil hydrochloride may include headache, constipation, swelling of the legs, fatigue, drowsiness, dizziness, redness of the skin, arrhythmia, allergic reactions and others. More serious side effects are also possible, so it is important to contact your doctor if you experience any unusual symptoms.

Verapamil hydrochloride is a prescription drug and should only be taken as directed by your doctor. The dosage and regimen depend on the specific condition of the patient and must be determined by the doctor.

It is important to consult a qualified healthcare professional for more information about verapamil hydrochloride, its uses, effects, and potential side effects.