Epistasis

Introduction

Epistatic interaction of genes is the interaction of two non-allelic genes, in which one of the genes suppresses the expression of alleles of this gene that are in different linkage pairs with it. Epistatic interactions of genes were first described in the 20th century by mathematician Robert Fisher in genetic populations while studying combinative variability



Epistasis is the interaction of genes with each other, leading to a change in their effect in cells. An example of epistasis is a set of genes that make a flower pink. But the color pink is obtained only if there is a dominant gene - the gene for white color and a recessive gene for coloring pink. Epistasis is considered to be a situation when a dominant weakens other genes. There are several types of epigenetics, but let's focus on the interaction of two dominant genes. Unfortunately, they do not “cancel” each other, but only switch to different parts of the chromosome.