Inhibitase

Inhibase: a drug for the treatment of arterial hypertension and chronic heart failure

Inhibase is a drug from the group of antihypertensive angiotensin-converting enzyme (ACE) inhibitors, which is produced in Switzerland by Makiz-Pharma and Hoffmann-La Roche. The main active substance is cilazapril, which is available in various dosage forms: film tablets 0.5, 1, 2.5 and 5 mg, as well as film-coated or conventional tablets.

Inhibase is used to treat arterial hypertension, including the renovascular form, as well as chronic heart failure as part of combination therapy with digitalis and/or diuretics. However, before starting treatment, it is necessary to ensure that there are no contraindications, such as hypersensitivity to ACE, a history of angioedema, pregnancy and breastfeeding.

Like any medicine, Inhibase may cause side effects. The most common of these are headache, dizziness, lethargy, dyspepsia and nausea. Problems with the cardiovascular and genitourinary systems, as well as allergic reactions, including angioedema, may also occur.

Inhibase may interact with other drugs, such as potassium-sparing diuretics, oral antidiabetic drugs and NSAIDs, which may increase or decrease its effect.

In case of an overdose of Inhibase, hypotension may occur, which is treated by increasing the volume of circulating blood. The medicine is partially eliminated from the body during hemodialysis.

It must be remembered that Inhibase has its own application features. Treatment is carried out under regular medical supervision, and if acute arterial hypotension occurs, it is necessary to take measures to increase the volume of circulating blood. In patients receiving diuretics, before starting treatment with Inhibase, the diuretic should be discontinued for 2-3 days. Hemodialysis through high-throughput polyacrylonitrite metall sulfate membranes (eg AN69), hemofiltration or LDL apheresis should also be avoided because anaphylaxis may develop.

In conclusion, we can say that Inhibase is an effective drug for the treatment of arterial hypertension and chronic heart failure. However, before starting treatment, you must consult your doctor and make sure there are no contraindications. It is also important to follow the instructions for use and not exceed the dosage. If side effects or unexpected reactions occur, you should consult a doctor to adjust the treatment.