Acrodermatitis Enteropathic

Acrodermatitis Enteropathic: Brandt and Danbolt-Kloss syndrome

Acrodermatitis enteropathica (ADE) is a disease that most often manifests itself in infants and is associated with zinc deficiency in the body. This disease is associated with metabolic disorders, especially carbohydrates and proteins, and can lead to various skin manifestations as well as gastrointestinal disorders.

Etiology and pathogenesis
ADE is caused by zinc deficiency in the body, which can be caused by insufficient intake of zinc from food or impaired absorption of zinc in the intestines. A lack of zinc leads to a decrease in the activity of many enzymes and metabolic disorders, especially carbohydrates and proteins.

Clinical picture
The main symptoms of ADE are vesicular, pustular, bullous dermatitis of the distal parts of the extremities, damage to the mucous membranes by yeast-like fungi, as well as gastrointestinal disorders (diarrhea, steatorrhea, profuse feces with an unpleasant odor). In the future, the disease can lead to malnutrition, secondary purulent infection, and growth retardation.

Diagnostics
The diagnosis of ADE is confirmed by the detection of low zinc levels in the blood. Differential diagnosis must be made with malabsorption syndrome and other dermatitis.

Treatment
The main drug for ADE is zinc sulfate in a dose of up to 100-150 mg per day for 2-3 months. The use of enzyme preparations is also recommended. With early recognition and treatment, the prognosis of the disease is favorable.

Prevention
To prevent ADE, it is necessary to follow feeding rules in accordance with the age of the child. The diet should contain sufficient amounts of zinc and other essential nutrients, and should be balanced and appropriate to the child’s age-related needs.

In conclusion, ADE is a serious disease that can lead to various complications. Therefore, it is important to consult a doctor in a timely manner and follow his recommendations for the treatment and prevention of this disease.



Title: Acrodermatitis is...?

**Acrodermatitis** is a group of skin diseases characterized by rashes mainly on the fingers and hands, and less often on other parts of the body. Acrodermatoses most often occur in young men, characterized by a chronic relapsing course. In patients with persistent allergic skin, acrodermatitis is formed as a result of allergic or paraallergic reactions. The main forms of these skin lesions are fixed and palmoplantar acrodermatitis, as well as acropyoderma.

Acrodermatosis, similar to many other dermatological diseases, differs from each other in the composition of its clinical manifestations. Skin lesions can affect both one part and all skin integuments. A total of three categories of body areas may be affected: scalp, face, neck, arms, legs and back. One of the main characteristic symptoms is a rash on the back of the hands. Based on the specific location of the rash, doctors divide acrodermatitis into several forms of the disease: fixed,



Acrodermatitis is a very common skin disease, affecting about 1-2% of the population in developed countries. Acrodermatitis with edema is a symptom of a systemic disease that affects various internal organs. This may be a lung disease (bronchial asthma), a disorder of the gastrointestinal tract