Diltiazem Hydrochloride

Diltiazem hydrochloride: description, use and side effects

Diltiazem hydrochloride is a calcium channel blocker of the benzodiazepine group and is used to treat various diseases of the cardiovascular system. In this article we will look at the main aspects of the use of this drug, as well as its side effects.

Manufacturers and dosage forms

Diltiazem hydrochloride is produced by two pharmaceutical companies - Confab (Canada) and Norton Healthcare Ltd (UK). The dosage form available for use is 60 mg tablets.

Composition and application

The active ingredient in Diltiazem is diltiazem hydrochloride. This drug is used for the treatment of angina, prevention of coronary spasm during coronary angiography or coronary artery bypass surgery, arterial hypertension, including after myocardial infarction, in patients with concomitant angina and diabetic nephropathy. Diltiazem hydrochloride is also used to relieve paroxysmal atrial fibrillation (in combination with digoxin), paroxysmal supraventricular tachycardia, and to prevent graft failure after kidney transplantation.

Contraindications and side effects

Diltiazem hydrochloride is contraindicated in cases of hypersensitivity, cardiogenic shock, left ventricular systolic dysfunction, sinus bradycardia, sick sinus syndrome, sinoatrial and AV block II-III degree, severe aortic stenosis, Wolff-Parconson-White and Lown-Ganong-Levine syndromes with paroxysms atrial fibrillation or flutter, impaired liver and kidney function, childhood, pregnancy and lactation.

Among the side effects of Diltiazem hydrochloride, transient hypotension, bradycardia, stage I conduction disturbance, decreased cardiac output, palpitations, fainting, eosinophilia, headache, dizziness, weakness, feeling of fatigue, peripheral edema, impaired potency, dyspeptic symptoms, mucosal hyperplasia may be observed. gums, sweating, redness of the skin, allergic reactions (skin rash and itching), rarely - exudative mu