Acetaminophen: description, uses and side effects
Acetaminophen, also known as paracetamol, is one of the most commonly used analgesics and antipyretics in the world. The drug was developed in the 1950s in the USA, where most of its production still takes place.
Acetaminophen belongs to the pharmacological group of analgesics-antipyretics, para-aminophenol derivatives. The drug is available in tablets of various strengths, including 325 mg and 500 mg.
Indications for the use of acetaminophen include pain of mild to moderate intensity, such as headaches, toothaches, migraines, back pain, arthralgia, myalgia, neuralgia, menalgia, and fever associated with colds.
However, before using the drug, it is necessary to take into account its contraindications. Acetaminophen should not be taken if you are hypersensitive to the components of the drug, with impaired renal or liver function, alcoholism, or in children under 6 years of age.
Like any drug, acetaminophen may cause side effects. Among the most common side effects are allergic reactions in the form of skin rashes, as well as hematopoietic disorders such as agranulocytosis, thrombocytopenia and anemia.
Interactions of acetaminophen with other medications also need to be considered. For example, acetaminophen increases the effect of indirect anticoagulants and the likelihood of liver damage from hepatotoxic drugs. Metoclopramide increases and cholestyramine reduces the rate of absorption. Barbiturates reduce antipyretic activity.
Acetaminophen overdose can cause severe liver and kidney damage, which can be fatal. Signs of overdose may include pallor, nausea, vomiting, abdominal pain, cardiac arrhythmias and pancreatitis.
In conclusion, acetaminophen is an effective analgesic and antipyretic. However, before using it, it is necessary to take into account contraindications and possible side effects. If any unpleasant symptoms occur, you should consult a doctor for consultation and treatment.