Acidosis

Acidosis is a pathological condition caused by the accumulation of acids in the body or excessive excretion of bases. It is characterized by an increase in the concentration of hydrogen ions in the blood and tissues (a decrease in pH).

With acidosis, the blood pH decreases below normal levels of 7.35-7.45. This leads to an imbalance in the acid-base balance and can negatively affect the functions of many organs and systems.

The causes of acidosis are varied. These include:

1. renal failure, which impairs the removal of acids from the body;

2. diabetes, leading to the accumulation of ketone bodies;

3. fasting, which enhances ketogenesis;

4. methyl alcohol poisoning, causing accumulation of lactic acid;

5. taking certain medications;

6. severe infections, etc.

Clinical manifestations of acidosis include nausea, vomiting, weakness, drowsiness, and shortness of breath. In severe cases, cardiac arrhythmias, coma, and death are possible.

To diagnose acidosis, a blood test is performed to measure pH, bicarbonate and other indicators of acid-base balance. Treatment is aimed at eliminating the cause of the disease and restoring normal blood pH using alkaline solutions, diet or medications. With timely treatment, the prognosis for acidosis can be favorable.

Acidosis is a disease characterized by a change in the internal environment of the body - a downward shift in the pH value. If the patient requires oxygen therapy, they speak of respiratory acidosis. When the body's pH drops below 7.2, respiratory acidosis (gas) is suspected.

Classification and diagnosis of acidosis

Aciduria occurs mainly in children in the first day of life, which is associated with pancreatic deficiency. There are several types of acidotic pathology that differ clinically from each other. * Signs of aciduria may occur for no apparent reason (for example, fetal hypoxia when it enters the mother’s respiratory tract). The risk of acidotic syndrome develops during the neonatal period (rapid metabolic changes are possible). This is the infant form of acidoma.

Pathology can manifest itself at any age. For example, if the kidneys suffer due to the developing process of transplant rejection. Acidosis accompanies renal toxemia, pancreatitis, chronic gastrointestinal insufficiency and endocrine pathology.