Акантоз (Acanthosis)

Acanthosis is a dermatosis characterized by thickening of the epidermis caused by an increase in the number of spinous cells in its germ layer. This disease can be either benign or malignant.

The most common form of acanthosis is Acanthosis nigricans, which is characterized by significant papillomatous growths, especially on the skin of the armpits. This leads to hyperpigmentation of the skin and its acquisition of a velvety shade. According to doctors, this disease is often accompanied by increased tolerance of the body to insulin.

However, not all cases of Acanthosis nigricans are associated with increased insulin tolerance. In some cases, this disease may be associated with the use of certain medications, as well as with a hereditary predisposition.

Another form of acanthosis is the benign form (Pseudoacanthosis nigricans), which is often associated with obesity. In this case, acanthosis can be caused by excessive tension of the skin, which leads to its thickening and acquiring a characteristic shade.

However, even though the benign form of acanthosis is not dangerous to health, doctors are still advised to visit them to rule out the possibility of other diseases that could lead to similar symptoms. If acanthosis is caused by medications, you should consult with a specialist to find out which medications may cause these side effects and what can be done to avoid them.

In general, acanthosis is a fairly common disease, but like many other dermatological diseases, it can be successfully treated with timely medical attention and appropriate treatment.



Acanthosis is a dermatological disease characterized by an increase in the number of spinous cells in the germinal layer of the epidermis, which leads to its thickening. It manifests itself as significant papillomatous growths, especially noticeable on the skin of the armpits, and is accompanied by hyperpigmentation of the skin and its acquisition of a velvety tint. Doctors also note that acanthosis is often associated with increased body tolerance to insulin. This condition is called Acanthosis nigricans.

Acanthosis can be either benign or malignant. However, in most cases, doctors have to deal with its benign form, known as Pseudoacanthosis nigricans, which is often associated with obesity.

Pseudoacanthosis nigricans usually develops as a result of insulin resistance, a condition in which the body becomes less sensitive to the effects of insulin. This can occur with obesity, metabolic syndrome, type 2 diabetes and other metabolic disorders. Obesity and associated insulin resistance promote increased epithelial growth processes and lead to the proliferation of spiny cells of the epidermis.

Pseudoacanthosis nigricans usually appears as thickening and darkening of the skin in folded areas such as the neck, armpits, elbows, and knees. The skin becomes hyperpigmented, rough and velvety to the touch. Although pseudoacanthosis nigricans usually does not pose a health threat, its presence may indicate the presence of other metabolic disorders such as diabetes or metabolic syndrome.

Treatment of acanthosis and pseudoacanthosis nigricans is aimed at eliminating the underlying disease causing insulin resistance. In case of obesity, weight loss through lifestyle changes, including proper nutrition and physical activity, is recommended. In some cases, medications may be prescribed to improve insulin sensitivity.

It is important to see a doctor to get an accurate diagnosis and prescribe the optimal treatment. He will be able to determine the form of acanthosis and conduct additional tests if necessary.

In conclusion, acanthosis is a dermatological disease characterized by thickening of the epidermis due to an increase in the number of spinous cells in its germinal layer. It can manifest itself in the form of significant papillomatous growths, especially noticeable in the armpits. Such changes in the skin are accompanied by hyperpigmentation and a velvety tint, which is known as Acanthosis nigricans. Doctors also note that this dermatosis is often accompanied by increased body tolerance to insulin.

Acanthosis can be either benign or malignant. However, the most common benign form is known as Pseudoacanthosis nigricans, which is often associated with obesity. Pseudoacanthosis nigricans usually develops as a result of insulin resistance, a condition in which the body becomes less sensitive to insulin. This condition can occur with obesity, metabolic syndrome, type 2 diabetes and other metabolic disorders. Increased epithelial growth processes and proliferation of epidermal spinous cells are associated with obesity and associated insulin resistance.

Pseudoacanthosis nigricans causes thickening and darkening of the skin in folded areas such as the neck, armpits, elbows and knees. The skin becomes hyperpigmented, rough and velvety to the touch. Although pseudoacanthosis nigricans is not usually a health threat, its presence may indicate the presence of other metabolic disorders such as diabetes or metabolic syndrome.

Treatment of acanthosis and pseudoacanthosis nigricans is aimed at eliminating the underlying disease causing insulin resistance. For obesity, weight loss through lifestyle changes, including proper nutrition and physical activity, is recommended. In some cases, medications may be prescribed to improve insulin sensitivity.

It is important to see a doctor to get an accurate diagnosis and prescribe the optimal treatment. The doctor will be able to determine the form of acanthosis and conduct additional tests if necessary.

In conclusion, acanthosis is a dermatological disease that is characterized by thickening of the epidermis



Acanthosis is an increase in the number (cellularity) of spiny skin cells under the upper layer of the epidermis, which leads to their concentrated accumulation in the upper layers of the skin and is sometimes accompanied by thickening of the skin. A type of this pathology is a characteristic darkish tint of the skin under the arms with its inclusion in the upper back and lateral parts of the chest - this is a characteristic sign of Acanthosis (or Acanthosismus niger).

Such changes are caused by excessive accumulation of elastin fibers in the subcutaneous layers of tissue, accompanied by accumulation of lipocytes in the dermis. Such a pathology can be either a manifestation of heredity or a symptom indicating certain diseases of the internal organs.

This phenomenon has the opposite meaning in the case when these areas of the skin sink, which usually causes a violation of the venous outflow. The same processes cause thickening of the walls of small blood vessels located close to the skin. This indicates a progressive stage