Acanthosis Proliferative

Acanthosis proliferative

Acanthosis proliferative is a pathological skin condition characterized by thickening of the epidermis (top layer of skin) due to excessive cell proliferation.

Causes

The main reason for the development of proliferative acanthosis is the increased proliferation of basal and spinous cells of the epidermis. This process can be caused by various diseases and conditions accompanied by inflammation and damage to the skin, in particular:

1. Psoriasis
2. Eczema
3. Allergic and contact dermatitis
4. Skin tumors
5. Skin infections
6. Injuries and burns

In these conditions, excessive stimulation of cell division in the basal layer of the epidermis occurs, which leads to increased formation of horny scales.

Symptoms

The main clinical manifestations of proliferative acanthosis:

1. Thickening and hardening of the skin
2. Peeling
3. Itchy skin
4. Redness and irritation of the skin

Diagnostics

The diagnosis of proliferative acanthosis is established on the basis of the clinical picture and the results of histological examination of a skin biopsy. Microscopy reveals thickening of the epidermis, hyperkeratosis, acanthosis and papillomatosis.

Treatment

Treatment of proliferative acanthosis is aimed at eliminating the underlying disease or condition that caused its development. Topical glucocorticosteroids, vitamin D, retinoids, and phototherapy may be used. In some cases, systemic therapy is required.

Forecast

The prognosis depends on the effectiveness of treatment of the underlying disease and prevention of relapses. With adequate therapy, the processes of proliferation and differentiation of epidermal cells normalize, inflammation and clinical manifestations of acanthosis disappear.

Acanthosis proliferative (APA) is a condition that occurs due to abnormal growth and excess cell division in the layer of skin called the epidermis. This process leads to the formation of large moles and spots on the skin.

In PA, cell growth occurs normally, but they multiply too quickly. This can lead to the development of abnormal cells that can become cancerous. PA can be caused by a number of diseases, including some forms of cancer, genetic mutations, and infections. Treatment of PA depends on the cause that caused its development.

Symptoms of PA may include: - Formation of large patches on the skin that grow over time. - The skin becomes rough and rough. - The spots may turn brown or black.

In general, a PA is not