Amlodipine

Country of origin: Russia, Makis-Pharma Russia, Obolenskoe pharmaceutical enterprise Russia

Pharm-Group: Calcium channel blockers of the dihydropyridine group

Manufacturers: Kanonpharma production (Russia), Makis-Pharma (Russia), Obolenskoye pharmaceutical enterprise (Russia)

International name: Amlodipine

Synonyms: Agen, Acridipine, Amlovas, Amlotop, Aronar, Vero-Amlodipine, Kalchek, Cardilopin, Corvadil, Norvadin, Norvasc, Normodipin, Omelar cardio, Stamlo, Tenox

Dosage forms: tablets 10 mg, tablets 5 mg

Composition: Active substance - Amlodipine.

Indications for use: Arterial hypertension, stable and vasospastic angina (Prinzmetal), including in patients resistant to therapy with nitrates or beta-blockers.

Contraindications: Hypersensitivity, arterial hypotension (less than 90 mm Hg), shock, acute myocardial infarction. Restrictions on use: severe aortic stenosis, heart failure, liver dysfunction, children's age (safety and effectiveness of use have not been determined).

Side effect:

1. From the cardiovascular system and blood: facial skin flushing, palpitations; rarely - rhythm disturbances, chest pain, hypotension (including orthostatic).

2. From the nervous system and sensory organs: fatigue, headache, dizziness, drowsiness; rarely - fatigue, asthenia, mood changes, visual disturbances.

3. From the genitourinary system: peripheral edema (swelling of the ankles and feet); rarely - increased frequency of urination, impotence.

4. From the gastrointestinal tract: nausea, abdominal pain; rarely - dyspepsia, change in bowel habits, jaundice.

5. From the respiratory system: rarely - shortness of breath.

6. From the musculoskeletal system: rarely - arthralgia, myalgia, paresthesia and pain in the extremities (with long-term use).

7. From the skin: rashes, itching, rarely - erythema multiforme.

8. Other: rarely - gingival hyperplasia, gynecomastia, increased levels of liver enzymes.

Interaction: Compatible with major groups