Ampicillin sodium salt is an antibiotic of the penicillin group.
general information
- Producing countries: Russia, Belarus, India, Italy
- International name: Ampicillin
- Trade names: Ampiside, Ampic, Ampirex, Ampicillin, Amplital, Apo-Ampi, etc.
- Dosage forms: powder for injection, substance
- Pharmacotherapeutic group: antibiotics of the penicillin group
Composition and release form
Active substance: ampicillin.
Available in the form of a powder for the preparation of an injection solution in dosages of 250 mg and 500 mg, as well as in the form of a substance and a sterile substance.
pharmachologic effect
Ampicillin is a broad-spectrum antibiotic from the penicillin group. It has a bactericidal effect by disrupting the synthesis of bacterial cell walls. Active against gram-positive and some gram-negative microorganisms.
Indications for use
Infectious and inflammatory diseases of the respiratory tract, ENT organs, genitourinary system, abdominal organs, skin and soft tissues, musculoskeletal system, meningitis, etc.
Contraindications
- Hypersensitivity to ampicillin and other penicillin antibiotics
- Severe liver failure
- Breastfeeding period
Side effects
- Dyspeptic disorders, dysbacteriosis
- Allergic reactions
- Superinfections caused by resistant microorganisms
Drug interactions
Reduces the effectiveness of oral contraceptives. Increases the effect of anticoagulants and aminoglycosides.
Overdose
It has a toxic effect on the central nervous system. Treatment: symptomatic.
special instructions
With prolonged use, the development of superinfections is possible. Additional intake of B vitamins, vitamin C, and antifungal drugs is recommended.
Sources
Encyclopedia of medicines Mashkovsky. Encyclopedia of drugs. Instructions for use of the drug Ampicillin.