Antiarrhythmic agent

An Anti-Arrhythmic drug is any of the medicinal substances used to restore cardiac arrhythmias (see Arrhythmia). Antiarrhythmic drugs include:

  1. Atropine, an alkaloid obtained from plants of the nightshade family, blocks m-cholinergic receptors and increases heart rate.

  2. Amiodarone is a synthetic class III antiarrhythmic drug that prolongs the action potential of cardiomyocytes.

  3. Verapamil is a slow calcium channel blocker that reduces the conductivity of the sinoatrial and atrioventricular nodes.

  4. Quinidine is an alkaloid of cinchona bark, blocks sodium channels of cardiomyocytes, prolongs the action potential.

  5. Disopyramide is a synthetic class I antiarrhythmic that suppresses the fast phase of depolarization of cardiomyocytes.

  6. Lignocaine is a local anesthetic that blocks sodium channels and shortens the action potential.

Each of these substances has its own characteristics of action and indications for use in various types of arrhythmias. Their appointment should be carried out strictly under the supervision of a cardiologist.



Antiarrhythmic drugs

A medicine used to restore irregular heart rhythms.

Arrhythmias are abnormal heart rhythms that can be caused by a variety of causes, including heart disease, electrolyte abnormalities, and other factors. Antiarrhythmic drugs are used to treat arrhythmias to prevent their development and improve heart rhythm.

There are several classes of antiarrhythmic drugs, each of which has its own characteristics and mechanisms of action. Some of the most common drug classes include:

1. Sodium channel blockers

These drugs block sodium channels in the heart, which reduces excitability and prevents arrhythmias. These include procainamide, quinidine and flecainide.

2. Potassium channel blocker

These medications reduce the amount of potassium that passes through cell membranes, which also reduces the irritability of the heart. Examples include amiodarone and sotalol.

3. Beta blockers

Beta blockers block the action of adrenaline on the heart, which lowers the heart rate and prevents arrhythmias. These drugs include propranolol, atenolol and metoprolol.

4. Antiarrhythmics acting through calcium channels

Drugs in this class reduce the amount of calcium that passes through calcium channels, which reduces excitability and prevents arrhythmias. Examples include verapamil and diltiazem.

It is important to note that the choice of antiarrhythmic drug depends on the type of arrhythmia being treated and the individual patient. Before starting treatment, you must consult your doctor and undergo an appropriate examination to determine the appropriate drug.



Antiarrhythmic drug (Antiarrhythmicum) is any drug intended to stabilize the heart rhythm after it has been disrupted. If arrhythmia occurs, then the patient has the feeling that the heart is not beating in the right rhythm. By “wrong” we mean a high pulse, irregular rhythm, or a low pulse. Many people confuse a number of conditions with the concept of arrhythmia. "Arrhythmia" can be called any abnormality of the pulse. These states are far from each other and may require completely different actions.

Regardless of the origin and severity, arrhythmia can cause the most unpleasant consequences, so it is necessary to combat this disease as early as possible. There are many classifications and types of arrhythmia, but in this article we will look at the main ones.

For example, atrial fibrillation is a rhythm disorder in which the heart rate more than doubles. This condition is dangerous