Country of origin - Russia
Pharm-Group - Immunoglobulins
Manufacturers - Russian Research Institute of Gerontology, Ministry of Health of the Russian Federation (Russia)
International name - Antithymocyte immunoglobulin
Synonyms - Antilympholin, Antilympholin Kr, ATG-Fresenius (Anti-human T-lymphocyte-globulin of rabbit), ATG-Fresenius S, Atgam, Thymoglobulin
Dosage forms - powder for the preparation of an injection solution 40 mg, powder for the preparation of an injection solution 70 mg
Composition - Antithymocyte immunoglobulin.
Indications for use: Kidney transplantation, prevention of graft rejection during skin grafting. Aplastic anemia in the absence of indications for bone marrow transplantation.
Contraindications - Hypersensitivity to the drug, pregnancy, lactation, childhood.
Side effects - Allergic reactions, thrombocytopenia, leukopenia, granulocytopenia, anemia, pancytopenia, enlarged or ruptured spleen, arterial hypertension, heart failure, pulmonary edema, nausea, vomiting, diarrhea, gastrointestinal bleeding, perforation of the stomach or intestines, ulceration of the oral mucosa , pain in the abdomen and epigastric region, headache, weakness, convulsions, confusion, loss of coordination, dizziness, fainting, paresthesia, swelling at the infusion site, thrombophlebitis, nosebleeds.
Interaction - No data available.
Overdose - No data available.
Special instructions - For use only in hospital settings. Treatment is stopped in the presence of a generalized rash, tachycardia, dyspnea, collapse, anaphylaxis, persistent leukopenia in patients with a kidney transplant. More detailed information can be found in the instructions for use of the drug.
Literature - Directory "Medicines", M. A. Klyuev, 2001.