Antistreptohyaluronidase

Antistreptohyaluronidase: role in the diagnosis of streptococcal infection

Streptococcal infection is one of the most common bacterial infections affecting humans. It causes many diseases, including pharyngitis, tonsillitis, scarlet fever, rheumatic fever and others. Various methods are used to diagnose streptococcal infection, including bacteriological studies and immunological tests.

One of the immunological tests widely used to diagnose streptococcal infection is based on measuring the level of antistreptohyaluronidase antibodies in the blood serum. Streptohyaluronidase is an enzyme secreted by streptococci that destroys hyaluronic acid, which is part of the intercellular substance. Antistreptohyaluronidase antibodies are formed in the body in response to streptococcal infection and have the ability to neutralize this enzyme.

Measuring the level of antistreptohyaluronidase antibodies in the blood serum has diagnostic value in assessing the presence or absence of streptococcal infection. A high level of these antibodies indicates the presence of infection, while a low level indicates its absence. Therefore, this test may be useful in confirming the diagnosis of streptococcal infection and selecting optimal therapy.

In addition, antistreptohyaluronidase antibodies may be useful in assessing the effectiveness of treatment for streptococcal infections. After starting treatment, the level of these antibodies may decrease, indicating regression of the infection. This may help decide whether to continue or discontinue therapy.

Thus, antistreptohyaluronidase antibodies are an important tool in the diagnosis and monitoring of streptococcal infections. Their measurement in serum can help decide the need and optimal duration of therapy, an important step in the fight against this common bacterial infection.