Antibodies Monovalent

Antibodies of monovalent type

Monovalent antibodies are monomeric antibody-like immunoglobulins that correspond in structure to one of the groups of blood plasma proteins. This immunoglobulin molecular class has only specific antibody groups on its surface, and only one type of them, i.e. single antigen binding sites. They have high affinity for their target due to the single group of functional specificity of the molecule. This feature determines the specificity of monovalent antibodies during their implementation. Thus, when using artificial analysis technology, in most cases, in the matter of recognizing a particular antigen, monospecificity is involved in terms of the antigen-antibody reaction. Another advantage of monovalent antibodies is their ability to exhibit slightly greater affinity for their target than representatives of the class of polyspecific antibodies. In addition, in the area of ​​influence it is worth highlighting their exclusively selective effect on the antigen, so that when usually used as indicators of a certain type of antigen, an extremely insignificant or completely absent “background” effect is observed for other antigens. Although this set of ingredients still cannot be attributed to obvious advantages, one cannot fail to mention the significant cost-effectiveness of this substance as part of an analytical system based on monovalent antibodies