Aspizol

Country of origin - Germany
Pharm-Group - Anti-inflammatory drugs - salicylic acid derivatives

Manufacturers - Bayer AG (Germany)
International name - Lysine acetylsalicylate
Synonyms - Acelizin, Inesprin, Laspal
Dosage forms - powder for the preparation of injection solution
Composition - Active ingredient - Lysine acetylsalicylate.

Indications for use:

1. Fever syndrome
2. Pain syndrome (including rheumatic pain)
3. Prevention of thrombosis

Contraindications:

1. Hypersensitivity
2. Peptic ulcer of the stomach and duodenum
3. Diseases accompanied by hemorrhagic syndrome
4. Pregnancy (3rd trimester)

Side effect:

1. Dyspeptic symptoms and ulcerative lesions of the gastrointestinal tract
2. Gastrointestinal bleeding
3. Hemorrhagic syndrome
4. Tinnitus, hearing loss, headaches
5. Allergic reactions (anaphylaxis, rash, bronchospasm, etc.)

Interaction:

1. Enhances the effect of methotrexate, oral hypoglycemic agents (sulfonylurea derivatives)
2. Weakens the effect of uricosuric drugs
3. Increases the risk of bleeding when used with anticoagulants

Overdose:
Symptoms: tinnitus, hearing loss, severe headaches.
Treatment is correction of acid-base balance (infusion of solutions of sodium bicarbonate, citrate, etc.).

Special instructions:

1. Prescribed with caution for gastroduodenal ulcerative diseases, renal failure, asthma, gout, menorrhagia, and the presence of an intrauterine contraceptive device.

Literature:
Encyclopedia of Medicines 2004