Country of origin - Germany
Pharm-Group - Anti-inflammatory drugs - salicylic acid derivatives
Manufacturers - Bayer AG (Germany)
International name - Lysine acetylsalicylate
Synonyms - Acelizin, Inesprin, Laspal
Dosage forms - powder for the preparation of injection solution
Composition - Active ingredient - Lysine acetylsalicylate.
Indications for use:
- Fever syndrome
- Pain syndrome (including rheumatic pain)
- Prevention of thrombosis
Contraindications:
- Hypersensitivity
- Peptic ulcer of the stomach and duodenum
- Diseases accompanied by hemorrhagic syndrome
- Pregnancy (3rd trimester)
Side effect:
- Dyspeptic symptoms and ulcerative lesions of the gastrointestinal tract
- Gastrointestinal bleeding
- Hemorrhagic syndrome
- Tinnitus, hearing loss, headaches
- Allergic reactions (anaphylaxis, rash, bronchospasm, etc.)
Interaction:
- Enhances the effect of methotrexate, oral hypoglycemic agents (sulfonylurea derivatives)
- Weakens the effect of uricosuric drugs
- Increases the risk of bleeding when used with anticoagulants
Overdose:
Symptoms: tinnitus, hearing loss, severe headaches.
Treatment is correction of acid-base balance (infusion of solutions of sodium bicarbonate, citrate, etc.).
Special instructions:
- Prescribed with caution for gastroduodenal ulcerative diseases, renal failure, asthma, gout, menorrhagia, and the presence of an intrauterine contraceptive device.
Literature:
Encyclopedia of Medicines 2004