Atheromatosis [Atheromatosis; Atheroma (Base Atheromat-) + -O]

Atheromatosis is a stage of development of an atherosclerotic plaque, which is characterized by the appearance of detritus (fine-grained particles) in its center. This detritus is formed as a result of the breakdown of lipid, protein, collagen, elastic fibers, as well as cholesterol crystals and fatty acids.

An atheromatous plaque is a dense formation consisting of several layers. In the center of the plaque there is detritus, which is the cause of its appearance. This detritus can be caused by various factors such as high blood cholesterol, smoking, diabetes and other diseases.

If atheromatous plaque is not treated, there is a risk of its rupture and blood clot formation. This can lead to serious consequences such as stroke or myocardial infarction. Therefore, it is very important to monitor your health and take measures to prevent atherosclerosis.



Atheromatosis is an inflammatory disease characterized by the appearance of lipogranulomas in the central parts of atheromas, caused by the breakdown of lipid-rich tissue, or the lack of treatment of atheromas, which leads to partial cell apoptosis and hyperplasia of surrounding tissues.

Cells of atheromatous tissue contain macrophages, connective tissue cells and fresh cell nuclei with remnants of decay products. Free radicals attack lipoproteins, oxidize cholesterol and convert it into peroxides and other oxidized products. When they are removed, the enzyme cholesterol esterase accumulates in the granuloma, which normally cannot be detected. This enzyme is kata