Autolysosome

"Autolysosomes: theory, practice and significance in biochemistry."

An autolysosome is a specialized membrane-bound space that is created inside a cell to complete the process of digestion and breakdown of macromolecules. The term Autolysosomes is derived from the Latin "auto" meaning "self" and the Greek word "lysos" meaning decomposition or digestion. These organelles play an important role in many biochemical processes, such as regulation of signal transduction and degradation of cell components.

The theory of autolysis.

The autolyssome process occurs in two stages. The first step is proteasome translocation, which transports membrane-bound components of the endoplasmic reticulum into the cell. Then there is an accelerated accumulation of these components, from which autolyssomar granules (AG) are formed. AG is a metabolic engine that accelerates metabolic processes in the cell. This is because AG contains a large number of short peptides that mediate many regulatory processes.

Many factors can influence the activation of the autolyssomoary process. For example, the p53 and FADD proteins block the process of activation of autolysmoar granules and serve as important regulators of circadian rhythms and the immune response. While many cytostatic drugs, such as antineoplastic drugs, can also affect the autolyssomal process, stimulating its destruction.

Evolution of autolysis processes. Autolsis reactions have their own evolutionary history. It has been established that autolytic reactions arise in the early periods of the emergence of life, including bacteria and archaea. Autolisome reaction was first identified in the bacterium Escherichia coli, in which it controls polyphosphate cycling. This mechanism was later found in a number of other prokaryotes and some eukaryotes. Autolysis reactions are one of the first known mechanisms of life cycle control, regulation of genetic material and cell resistance to stress. The biochemical mechanisms associated with these processes have played a huge role in accelerating human evolution and intelligence.

Currently, autolysis reactions are used in various forensic techniques, where they are determined by analyzing the expression of proteins at crime scenes. The biological significance of autolysis reactions goes beyond forensic research and is used in medicine, ensuring the proper functioning of biological systems and maintaining health.