Bactrim

Bactrim: use, contraindications and side effects

Bactrim is a combination antimicrobial agent used to treat various infections caused by bacteria. It consists of sulfamethoxazole and trimethoprim and is available in various dosage forms such as tablets, syrups and injections.

Manufacturers of Bactrim include ICN Galenica from Yugoslavia, Roche Pharma Switzerland, Hoffmann-La Roche Switzerland and Hoffmann-La Roche Turkey. Its international name is Co-trimoxazole, and there are also several synonyms such as Biseptol, Bicotrim and Intrim.

Bactrim is used to treat respiratory tract infections, urinary tract infections, urogenital infections, gastrointestinal infections, skin and soft tissue infections, as well as to prevent relapses of bronchitis. It may also be used to treat infections caused by Pneumocystis carinii in patients with AIDS.

However, like any other medication, Bactrim has contraindications and can cause side effects. Contraindications include hypersensitivity to sulfonamides or trimethoprim, liver or renal failure, B12 deficiency anemia, agranulocytosis, leukopenia, glucose-6-phosphate dehydrogenase deficiency, pregnancy, breastfeeding, childhood and hyperbilirubinemia in children.

Side effects may include dyspepsia, nausea, vomiting, anorexia, increased transaminases and bilirubin, pancreatitis, stomatitis, glossitis, agranulocytosis, anemia, thrombocytopenia, hypoprothrombinemia, methemoglobinemia, eosinophilia, crystalluria, renal failure, interstitial nephritis, toxic nephropathy with oliguria and anuria .

In general, Bactrim is an effective treatment for infections, but should only be prescribed after consultation with a doctor and taking into account the individual characteristics of the patient. Patients should monitor for possible side effects and seek medical attention if they occur.