Basophil: role in the immune system and connection with allergies
Basophils are a type of white blood cell, or leukocyte, that plays an important role in the human immune system. They got their name due to the special color that they acquire when special dyes are used in the laboratory.
Basophils are part of a group of cells called granulocytes, which also include neutrophils and eosinophils. Like these cells, basophils contain granules in their cytoplasm that can be released when the cell is activated.
Basophils play an important role in the immune system as they are key players in the development of allergic reactions. When basophils are activated, they release chemicals such as histamine and leukotrienes, which can cause allergy symptoms such as itching, redness, swelling and excessive watery eyes. In addition, basophils can attract other immune system cells to the site of infection or inflammation, which helps fight infection or injury.
Although basophils play an important role in the immune system, their precise function is still not fully understood. Research is ongoing, and scientists hope to uncover additional aspects of the role of basophils in the near future.
In addition, basophils may also play a role in the development of autoimmune diseases such as rheumatoid arthritis. Some studies have shown that basophils may increase the inflammatory response in the joints, which may contribute to the development of the disease.
Although the role of basophils in the development of allergic reactions has been well studied, the mechanisms that lead to their activation within allergies are still not fully understood. However, thanks to scientific efforts, including animal studies and cellular models, we are beginning to better understand the role of basophils in health and disease.