Pregnancy Immunoconflict

An immunocompromised pregnancy (also known as an immunologically incompatible pregnancy) is a condition where the immune systems of the mother and fetus are in conflict with each other. This conflict can arise due to various genetic factors, including heredity and differences in the genome of the mother and fetus.

When a woman becomes pregnant, her immune system begins to produce antibodies that can be directed against the fetus because it perceives it as a foreign body. In response to this, the fetus's immune system also begins to produce its own antibodies, which can attack the mother's tissue.

One of the most common examples of immunoconflict pregnancy is Rhesus conflict. If the mother has Rh negative blood and the fetus inherits Rh positive blood from the father, the mother's immune system may begin to produce antibodies against the fetal blood. This can lead to fetal anemia and other pregnancy complications.

Another example of an immunoconflict is a blood group conflict. If the mother has type A blood and the fetus has type B blood, the mother's immune system may begin to produce antibodies against the fetal blood. This can lead to hemolytic disease of the newborn, which can be life-threatening to the fetus.

To prevent pregnancy complications, immunocompromised women are advised to undergo regular screening during pregnancy and receive appropriate treatment if necessary. In some cases, fetal blood transfusion or maternal-fetal plasma exchange may be required to reduce antibody levels.

In conclusion, an immunocompromised pregnancy can be dangerous to the health of the mother and fetus, so it is important to promptly seek medical help and monitor your health during pregnancy.