Bergonier-Tribondeaux Rule

Bergonier-Tribondeaux Rule: Fundamentals and Applications in Radiology and Oncology

In the world of medicine and radiology, there are many rules and principles that help in understanding and assessing various aspects of diseases, including tumors. One such important rule is the Bergonier-Tribondeaux Rule, named after the French doctors Georges Henri Bergonier and Louis Marie Ferdinand Antoine Tribondeaux.

Bergonier and Tribondeau conducted research in the early 20th century to better understand the effects of radiation on living tissue. They found that different cell types have different sensitivity to radiation. Their observations led to the formulation of the Bergonier-Tribondo Rule, which predicts the likelihood of radiation damage occurring depending on the type of tissue and exposure conditions.

The main idea of ​​the Bergonier-Tribondo Rule is the following: the more cells that multiply and the lower their differentiation, the more sensitive they become to radiation. In other words, cells that are actively dividing and are not fully specialized are more susceptible to radiation and are more likely to be damaged.

This rule has application in various fields of medicine, especially in radiology and oncology. In radiology, it assists in the planning and delivery of radiotherapy, where determination of radiation dose and selection of appropriate radiation techniques are critical. Using the Bergonier-Tribondo Rule, radiologists can predict which tissues will be more or less sensitive to radiation and adapt their radiation strategies based on this information. For example, tumors with high levels of cell proliferation and low differentiation may require a higher dose of radiation to achieve effective tumor control.

In oncology, the Bergonier-Tribondeaux Rule can also be used to classify tumors and predict their response to radiotherapy. Tumors that comply with the basic principles of the rule will be more sensitive to radiation and therefore more susceptible to destruction. This allows oncologists to make more informed treatment decisions and predict the likelihood of a successful outcome.

However, it should be noted that the Bergonier-Tribondeaux Rule is not universal and does not apply in all cases. Its applicability is limited to certain tumor types and radiation conditions. It is also worth considering that there are other factors that influence the effectiveness of radiotherapy, such as the size of the tumor, its location and the general condition of the patient.

The Bergonier-Tribondeaux Rule remains an important tool in radiology and oncology to improve the understanding and prediction of the response of living tissue to radiation. Further research and development will expand our knowledge of this rule and its application, which will ultimately lead to improved cancer treatment and increased effectiveness of radiotherapy.



Bergonier and Tribondeaux proposed their rule in 1908 as a way to define disease and assess prognosis. This rule consists of a combination of clinical manifestations and laboratory tests for the purpose of diagnosis and treatment. The diagnosis is made based on three criteria: the size and color of the red spot on the skin; the presence of inflammatory changes in the lymph nodes; symptoms of intoxication and fever.

Bergonier believed that the prognosis of the disease depends on many factors, including age, general health, location and size of the lesion, and the presence of concomitant diseases. Tribondo noted that it is important to consider social aspects, such as access to health care and living conditions.

The Bergonier-Tribondo rule has become widely used in medicine and has not lost its relevance to this day. This is an important addition to the traditional diagnosis and treatment of infectious diseases, allowing a more accurate determination of the severity of the disease and the selection of the correct treatment tactics.