Betanaze

Betanase: an antidiabetic drug from India

Betanase (international name - glibenclamide) is an antidiabetic drug from the group of sulfonylurea derivatives. This drug is produced by the Indian company Kadila Pharmaceuticals and is used to treat type 2 diabetes mellitus when it is impossible to compensate for hyperglycemia with diet, weight loss and physical activity.

Betanase is available in the form of 5 mg tablets containing the active ingredient - glibenclamide. The drug is contraindicated in case of hypersensitivity to sulfonamide drugs, thiazade diuretics, diabetic precomatous and comatose state, ketoacidosis, extensive burns, surgical interventions and injuries, intestinal obstruction, gastric paresis, conditions accompanied by impaired absorption of food, the development of hypoglycemia (infectious diseases, etc.), hypo- or hyperthyroidism, impaired liver and kidney function, leukopenia, type 1 diabetes mellitus, pregnancy and lactation.

Like any medicine, Betanase may cause side effects. These may include disorders of hematopoiesis, hemostasis, headache, dizziness, changes in taste, hypoglycemia, proteinuria, porphyria cutanea tarda, liver dysfunction, cholestasis, dyspepsia, skin rashes and others.

It is important to note that Betanase may interact with other drugs. Thus, systemic antifungals (azole derivatives), fluoroquinolones, tetracyclines, chloramphenicol (inhibits metabolism), H2-blockers, beta-blockers, ACE inhibitors, NSAIDs, MAO inhibitors, clofibrate, bezafibrate, probenecid, paracetamol, ethionamide, anabolic steroids, pentoxifylline, allopurinol, cyclophosphamide, reserpine, sulfonamides, insulin can potentiate hypoglycemia, and barbiturates, phenothiazines, diazoxide, glucocorticoid and thyroid hormones, estrogens, gestagens, glucagon, adrenomimetic drugs, lithium salts, nicotinic acid derivatives and saluretics - weaken hypoglycemic effect.

In conclusion, we can say that Betanase is one of the drugs used to treat type 2 diabetes mellitus. However, before using it, you must carefully study the instructions for use and consult your doctor, since the drug has a number of contraindications and may cause side effects. It is also important to consider possible interactions with other drugs.