Blood Coagulation, Blood Clotting

Blood coagulation (Blood Clotting) is an important process that plays a key role in stopping bleeding and maintaining the integrity of our body. When a blood vessel or soft tissue is damaged, blood clotting begins immediately to prevent more blood loss.

Blood clotting occurs through the interaction of many different substances known as coagulation factors. These coagulation factors are in an inactive form in the blood and are activated only when the integrity of blood vessels or tissues is damaged.

There are two main blood coagulation systems - the internal system (intrinsic system) and the external system (extrinsic system). The internal system is activated when blood comes into contact with the damaged inner surface of the vessel, and the external system is activated when the integrity of the soft tissue is violated.

When coagulation factors are activated, thrombokinase releases the plasma protein prothrombin, which is converted into thrombin. Thrombin, in turn, converts fibrinogen, a blood protein dissolved in plasma, into insoluble fibrin. Fibrin fibers form the basis of a blood clot, which closes the damaged area of ​​the vessel or tissue and prevents further blood loss.

In addition, blood clotting includes other important components such as platelets and the fibrinolytic system. Platelets are blood cells that play a key role in the formation of blood clots and speeding up the blood clotting process. The fibrinolytic system is responsible for dissolving blood clots and restoring blood flow after the damaged area of ​​the vessel or tissue has healed.

Overall, the blood clotting process is a complex and well-coordinated mechanism that allows our body to cope with potentially dangerous blood loss. Despite this, disturbances in this process can lead to serious diseases such as thrombosis or hemophilia. Therefore, it is important to monitor your health and consult a doctor if you suspect any abnormalities in the blood clotting process.



Blood coagulation is one of the most important physiological mechanisms for healing damaged tissue in the animal body. This process gets its name from the Latin “coagulatio”, which means “coagulation” (from the Latin coagulo - “I thicken”).

The coagulation process is a natural form of the body’s protective reaction when tissue defects cannot be promptly processed by the system that ensures its integral structure. It provides rapid sealing of holes and wounds and helps stop bleeding. When blood clotting is activated, the natural process of fibrillation, also known as fibrillation, is altered to form insoluble fibrin from soluble fibrinogen, forming a “bolus” or scaffold around the bleeding. This process also further destroys healthy tissue and sometimes leads to inflammation of nearby tissue.

Thus, blood clotting is a physiological and necessary process. And disturbances and disturbances in the coagulation process in the physiological mechanism can cause serious illnesses and even lead to death. A bleeding disorder is manifested by the fact that the blood in the vessels does not clot, and between the walls of the vessels there are traces of active hemorrhage (hemorrhage) and bleeding may



Blood clotting is a process that takes place in the human body, which helps prevent the loss of significant volumes of blood and maintain the required level of blood pressure. This is accomplished due to the body’s ability to create blood clots (thrombi) at the site of damage to the vessel wall.

The blood clotting process consists of several stages. If damage occurs in a blood vessel, for example due to injury, then the nearby blood vessel contains a special protein - fibrinokin, which activates blood clotting factors. These factors are activated immediately after contact with the body.

The first step in the formation of a blood clot is the activation of protein clotting factors (prothrombin) and its conversion into thrombin. This protein enzyme is responsible for further transformations that occur during the formation of a blood clot and convert fibrinogen into fibrin, which becomes the basis for the formation of a blood clot. Fibrin forms an insoluble fibrous structure that prevents bleeding. This whole procedure takes only a few minutes, and the thrombus