The Boivin method refers to biological and immunological tests developed by the French microbiologist Albert Bovin in the 20s of the last century. The Boivin method is one of the early tests for identifying sensitization of the body to tuberculosis antigens, performed using tuberculin. This test is widely used in many countries around the world.
The first studies on the action of tubercurin were carried out by French scientists, among whom were Kohler, Vrivolde and Debelof in 1907. Due to the widespread use of tuberculosis and its epidemic spread in Europe, doctors were actively looking for new methods to combat this disease.
The development of tuberculosis puzzled doctors, since there was no universal test that would allow diagnosing this disease in all people. Gender and age groups did not matter; tuberculosis affected everyone. The first test carried out by Kohler could not give the correct result. The effectiveness of the new test immediately aroused suspicion, since after the children woke up, their parents and school staff stated that their child had absolutely no reaction to Koller’s test, but when examined by a doctor, they complained about his reaction. The test was imperfect and there were many violations in the technique itself.